A Literature Review of Factors Affecting Low Birth Weight Babies (LBW)
DOI:
https://doi.org/10.70062/globalhealth.v2i4.251Keywords:
Antenatal Care, Low Birth Weight, Maternal Nutrition, Pregnancy, Risk FactorsAbstract
Low Birth Weight (LBW) remains a critical global health issue that significantly contributes to neonatal morbidity and mortality, particularly in developing countries such as Indonesia. The main challenge in addressing LBW lies in its complex and multifactorial risk profile, which involves biological, social, environmental, and healthcare-related determinants. This study aims to analyze and synthesize the risk factors associated with LBW based on recent scientific literature. A literature review method was applied by searching articles from Portal Garuda, DOAJ, PubMed, and Google Scholar published between 2020 and 2025 using relevant keywords. The findings indicate that maternal age, interpregnancy interval, nutritional status, anemia, preeclampsia, infections, socioeconomic conditions, environmental exposure, and the quality of antenatal care are significant determinants of LBW. The synthesis of evidence confirms that LBW is influenced by the interaction of multiple individual and healthcare system factors rather than a single cause. In conclusion, this study highlights the urgent need to strengthen antenatal care services, improve maternal nutritional status, control maternal diseases during pregnancy, and implement community-based promotive and preventive strategies as key efforts to reduce the incidence of LBW.
References
Abitbol, C. L., & Rodriguez, M. M. (2012). The long-term renal and cardiovascular consequences of prematurity. Nature Reviews Nephrology, 8(5), 265–274. https://doi.org/10.1038/nrneph.2012.38
Alfira, J., Baliwati, Y. F., & Riyadi, H. (2025). Unveiling the risks of low birth weight prevalence: An ecological study in West Java. AcTion: Aceh Nutrition Journal, 10(1), 1–13. https://doi.org/10.30867/action.v10i1.2144
Andini, R. N., & Agustin. (2025). Faktor-faktor yang berhubungan dengan kejadian berat badan lahir rendah (BBLR) di RSUD Depati Hamzah Pangkalpinang tahun 2024. Jurnal Kesehatan Tambusai, 6(1), 1231–1243.
Arabzadeh, H., Doosti-irani, A., Kamkari, S., Farhadian, M., Elyasi, E., & Mohammadi, Y. (2024). The maternal factors associated with infant low birth weight: An umbrella review. BMC Pregnancy and Childbirth, 24(316), 1–11. https://doi.org/10.1186/s12884-024-06487-y
Belete, N. K., Belete, A. G., & Assefa, D. T. (2025). Effects of maternal anemia on low-birth-weight in Sub-Sahara African countries: Systematic review and meta-analysis. PLOS One, 20(6), 1–14. https://doi.org/10.1371/journal.pone.0325450
Blencowe, H., Krasevec, J., De Onis, M., Black, R. E., An, X., Stevens, G. A., Borghi, E., Hayashi, C., Estevez, D., Cegolon, L., Shiekh, S., Hardy, V. P., Lawn, J. E., & Cousens, S. (2025). National, regional, and worldwide estimates of low birthweight in 2015, with trends from 2000: A systematic analysis. The Lancet Global Health, 7(7), e849–e860. https://doi.org/10.1016/S2214-109X(18)30565-5
Fan, C., Huang, T., Cui, F., Gao, M., Song, L., & Wang, S. (2015). Paternal factors to the offspring birth weight: The 829 birth cohort study. International Journal of Clinical and Experimental Medicine, 8(7), 11370–11378.
Ghosh, R., Causey, K., Burkart, K., Wozniak, S., Cohen, A., & Brauer, M. (2021). Ambient and household PM2.5 pollution and adverse perinatal outcomes: A meta-regression and analysis of attributable global burden for 204 countries and territories. PLOS Medicine, 18(9), 1–22. https://doi.org/10.1371/journal.pmed.1003718
Herwanto, E. S., Hudiyanto, P. S., & Muhammad, I. (2024). Factors of maternal influence on low birth weight. Asian Journal of Health Research, 3(1), 30–35. https://doi.org/10.55561/ajhr.v3i1.144
Huang, X., Liu, J., Qi, L., Adachi, J. D., Wu, J., Li, Z., Meng, Q., Li, G. Y. H., Irene, M., & Lara, B. (2022). Birth weight and the risk of cardiovascular outcomes: A report from the large population-based UK Biobank cohort study. Frontiers in Cardiovascular Medicine, 9(827491), 1–9. https://doi.org/10.3389/fcvm.2022.827491
Ilmiani, T. K., & Iqbal, M. (2024). Faktor-faktor yang memengaruhi kejadian berat badan lahir rendah (BBLR) di RSIA Puri Betik Hati Bandar Lampung. Jurnal Kesehatan Dan Teknologi Medis, 8(10), 1–8.
Indah, N. S., Tiwery, B., S. Kep, M. Kep, & Sp Kep A. (2024). Edukasi dan upaya pencegahan stunting. In Book Chapter Stunting.
Irawati, D., Dewi Sartika, R. A., Utari, D. M., & Wirawan, F. (2024). Determinant factors of the incidence of low birth weight in Central Java province: Analysis of 2018 Basic Health Research data. Indonesian Journal of Public Health Nutrition (IJPHN), 4(2). https://doi.org/10.7454/ijphn.v4i2.8062
Kemenkes. (2023). Laporan statistik hayati Indonesia 2019-2023. Kementerian Kesehatan Republik Indonesia.
Kitengie, B. L., Ngiele, C. M., Salamayi, Y. S., Kitunga, C. K., Lutumba, B. B. L., Kafinga, E. L., Mawunu, M., Mudogo, V., Ngbolua, K. N., & Mukandu. (2024). Assessment of the risk factors for low birth weight at Kitenge Hospital, Mbujimayi City, Democratic Republic of the Congo: 2018-2022. Journal of Oral & Public Health, 5(3), 1–8. https://dx.doi.org/10.4314/orapj.v5i3.25
Krasevec, J., Blencowe, H., Coffey, C., Okwaraji, Y. B., Estevez, D., Stevens, G. A., Ohuma, E. O., Conkle, J., Gatica-Domínguez, G., Bradley, E., Muthamia, B. K., Dalmiya, N., Lawn, J. E., Borghi, E., Hayashi, C., Duncan, J. R., & Brook, C. A. (2023). Study protocol for UNICEF and WHO estimates of global, regional, and national low birthweight prevalence for 2000 to 2020. Gates Open Research, 6(80), 1–24.
Kumar, S., Ram, D., Baral, J. R., Raj, D., Kumar, N., & Gurung, G. (2022). Maternal hemoglobin and risk of low birth weight: A hospital-based cross-sectional study in Nepal. Heliyon, 8(January), e12174. https://doi.org/10.1016/j.heliyon.2022.e12174
Kurniasari, L., Kartasurya, M. I., Nugraheni, S. A., & Agushybana, F. (2024). Determinants for low birth weight in mothers giving birth during the Covid-19 pandemic. Amerta Nutrition, 8(1), 27–36. https://doi.org/10.20473/amnt.v8i1SP.2024.27
Laksono, A. D., Wulandari, R. D., Matahari, R., & Laksono, A. D. (2023). Socioeconomic disparities in low birth weight in Indonesia’s rural areas: A population-based study. Atlantis Press, 12(4). https://doi.org/10.2991/978-94-6463-112-8
Libretti, A., Savasta, F., Nicosia, A., Corsini, C., De Pedrini, A., Leo, L., Simone, A., Tro, L., Dellino, M., Tinelli, R., Sorrentino, F., & Remorgida, V. (2024). Exploring the father’s role in determining neonatal birth weight: A narrative review. Medicina, 60(1661), 1–12. https://doi.org/10.3390/medicina60101661
Low, Preventing, Birthweight Committee, Low Birthweight, Health Promotion, Disease Prevention. (1985). Preventing low birthweight. National Academies Press.
Mare, K. U., Gobena Andarge, G., Sabo, K. G., & Mohammed, O. A. (2025). Regional and sub-regional estimates of low birth weight and its determinants in 44 low- and middle-income countries: Evidence from demographic and health survey data. BMC Pediatrics, 25(342). https://doi.org/10.1186/s12887-025-05691-9
Marlina, R., & Idealistiana, L. (2024). Analisis faktor resiko terjadinya BBLR (berat badan lahir rendah) pada bayi baru lahir di RS Citra Sari Husada Karawang. MANUJU: MALAHAYATI NURSING JOURNAL, 6(10), 4177–4189.
Mirnawati, M., Hasbullah, A. A., & Hariadi, A. (2025). Faktor-faktor yang ada hubungan dengan ibu yang melahirkan bayi berat badan lahir rendah di RSUD Dr. La Palaloi periode Januari 2023. Bosowa Medical Journal, 3(1), 18–22. https://doi.org/10.56326/bmj.v3i1.2481
Negrato, C. A., & Gomes, M. B. (2013). Low birth weight: Causes and consequences. Diabetology & Metabolic Syndrome, 5(49), 1–8.
Nurwati, Y., Hardinsyah, H., Marliyati, S. A., & Santoso, B. I. (2023a). A review of nutritional and health risk factors for low birth weight infants in Indonesia. Journal Gizi Pangan, 18(28), 22–24.
Nurwati, Y., Hardinsyah, H., Marliyati, S. A., & Santoso, B. I. (2023b). Potential maternal risk factors for low birth weight in Indonesia: A systematic review. Journal Gizi Pangan, 18(3), 167–176. https://doi.org/10.25182/jgp.2023.18.3.167-176
Odongkara, B., Nankabirwad, V., Achora, V., Arach, A. A., Napyo, A., Musaba, M., Mukunya, D., Ndeezi, G., Tylleskär, T., & Tumwine, J. K. (2024). Low birthweight increased the risk of neonatal death twenty-folds in northern Uganda: A community-based cohort study. MedRxiv. https://doi.org/10.1101/2024.04.25.24306373
Oktriyanto, M. B. R., Nury FN, D., Amrullah, H., & Pujihasvuty, R. (2022). Determinants of low birth weight in Indonesia. Jurnal Kesehatan Masyarakat, 17(4), 583–593.
Pancawardani, R., Amelia, R., & Wahyuni, S. (2020). Usia kehamilan ibu mempengaruhi keluaran bayi berat badan lahir rendah. Midwifery Care Journal, 3(2). https://doi.org/10.31983/micajo.v3i2.8312
Preventable, Ending. (2025). How we act now will determine the course. Ending Preventable Newborn Deaths and Stillbirths by 2023.
Qur, N., Fitriani, U., Dina, P., Cindra, F., Hutton, A., & Sweet, L. (2025). Multilevel modelling of the determinants of low birth weight in frontier, outermost and underdeveloped regions: Evidence from the Indonesian National Socioeconomic Survey (2019–2021). Midwifery, 138, 104136. https://doi.org/10.1016/j.midw.2024.104136
Rizkika, A., Rahfiludin, M. Z., & Asna, A. F. (2023). Low birth weight related factors at Kertek 2 Public Health Centre Wonosobo Regency. Amerta Nutrition, 7(1), 37–44. https://doi.org/10.20473/amnt.v7i1.2023.37-44
Salim, P. R., Insani, N. D., & Sihaloho, E. D. (2024). Cost-analysis of reducing mortality rate for LBW babies at Fatmawati Hospital’s NICU. Indonesian Journal of Health Administration, 12(1). https://doi.org/10.20473/jaki.v12i1.2024.129-138
Sari, D. P., Ekoriano, M., Pujihasvuty, R., Kistiana, S., Nasution, S. L., Ardiana, I., Purwoko, E., Devi, Y. P., & Muthmainnah, M. (2024). Antenatal care utilization on low birth weight children among women with high-risk births. F1000Research, 12(399), 1–20.
Tatiana, C., Garcia Barreto, F., Tavares, G. T., Theme-filha, M., Nascimento Farias, Y., Pantoja, L. D. N., & Cardoso, A. M. (2020). Low birthweight, prematurity, and intrauterine growth restriction: Results from the baseline data of the first indigenous birth cohort in Brazil (Guarani Birth Cohort). BMC Pregnancy and Childbirth, 20(784), 1–19. https://doi.org/10.1186/s12884-020-03396-8
Tee, J., Suryawan, I. W. B., & Suryaningsih, P. S. (2023). Risk factors influencing the incidence of low birth weight infants at Wangaya Regional General Hospital, Denpasar City, Bali. International Journal of Research and Review, 10(12).
Verina, Y., & Kartini, F. (2025). Methods of early detection for low birth weight (LBW) babies: A scoping review. MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN, 35(1), 169–179. https://doi.org/10.34011/jmp2k.v35i1.2565
WHO. (2021). Global nutrition targets 2025: Low birth weight policy brief. World Health Organization.
WHO. (2025). Low birth weight: What is this indicator? Nutrition Landscape Information System. World Health Organization.
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